Tick saliva discovery could be key to treating blood and immune disorders
The discovery of how the proteins in a tick’s saliva stop a human’s immune system from running amok could be the answer to treating life-threatening blood disorders, researchers say.
When a tick attaches to a human, it injects a substance that blocks immune receptors, which allows it to remain there without being rejected for up to 10 days, as it feeds on blood. Thus the ticks had found a way to evade the human immune system. These proteins that the ticks evolved can be used to inhibit a system called complement and this system can run amok in a number of diseased conditions including some life threatening blood disorders and some rare genetic kidney disorders.
Among those is one known as Paroxysmal Nocturnal Hemoglobinuria (PNH), which is life threatening and causes the immune system to attack and destroy blood cells. Thanks to this new discovery, the scientists hope this new understanding about proteins will help to bring the treatment cost down (currently $500,000 a year, per patient), as new treatments are developed.
The joint study will appears in the latest edition of Nature Structural and Molecular Biology journal.
Source : abc.net
Image : Photo by Jachan DeVol on Unsplash
High-quality writing is very important to members of the Global Goodness team. But no one’s perfect, so they always use Antidote to correct their texts.
Become an agent of change by contributing to the development of Global Goodness
All our costs are met by donations we receive from our users. If you enjoy positive news, please donate to support us.
Contact name: Global Goodness
Mobile: (514) 966 4544
Branch : 815 – Transit : 3019 – Account : 815 30197 891267
Beneficiary Name: Global Goodness
Beneficiary address: 4543 Fabre, Montreal, QC, H2J 3V7